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Genericname :   Nalbuphine {Injection}
Proununcation :   nal byoo feen
Brandname :   Nubain
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About youtreatment
Your doctor has ordered nalbuphine, an analgesic (painkiller), to relieve your pain. The drug will be injected into a large muscle (such as your buttock or hip), under your skin, or into a vein.You will probably receive nalbuphine every 3 to 6 hours as needed for pain. Your doctor may also order other pain medications to make you more comfortable. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.Your health care provider (doctor, nurse, or pharmacist) may measure the effectiveness and side effects of your treatment using laboratory tests and physical examinations. It is important to keep all appointments with your doctor and the laboratory. The length of treatment depends on how you respond to the medication.

Precautions
Before administering nalbuphine,

  • tell your doctor and pharmacist if you are allergic to nalbuphine, medications containing sulfites, or any other drugs.
  • tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially antidepressants; medications for cough, cold, or allergies; naloxone (Narcan); naltrexone (ReVia); other pain relievers; sedatives; sleeping pills; tranquilizers; and vitamins.
  • tell your doctor if you have or have ever had breathing difficulties, including asthma and other respiratory diseases, liver or kidney disease, severe inflammatory bowel disease, or a history of drug dependence.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking nalbuphine, call your doctor.
  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking nalbuphine.
  • you should know that this drug may make you drowsy. Do not drive a car or operate machinery until you know how nalbuphine will affect you.
  • remember that alcohol can add to the drowsiness caused by this drug.
    Administering your medication
    Before you administer nalbuphine, look at the solution closely. It should be clear and free of floating material. Observe the solution container to make sure there are no leaks. Do not use the solution if it is discolored, if it contains particles, or if the container leaks. Use a new solution, but show the damaged one to your health care provider.It is important that you use your medication exactly as directed. Nalbuphine can be habit forming. Do not administer it more often or for a longer period than your doctor tells you. Do not change your dosing schedule without talking to your health care provider.Side effects
    Although side effects from nalbuphine are not common, they can occur. Tell your doctor if any of these symptoms are severe or do not go away:
  • dizziness
  • lightheadedness
  • drowsiness
  • upset stomach
  • vomiting
  • dry mouth
  • headache
  • stomach cramps
  • itchy skin
  • bitter taste
  • confusion or hallucinations
  • feeling of heaviness
  • unusual weakness
    If you experience either of the following symptoms, call your doctor immediately:
  • difficulty breathing
  • fainting
    Storing your medication
  • Your health care provider will probably give you a several-day supply of nalbuphine at a time and provide you with directions on how to prepare each dose. Store the vials at room temperature.
    Store your medication only as directed. Make sure you understand what you need to store your medication properly.Keep your supplies in a clean, dry place when you are not using them, and keep all medications and supplies out of the reach of children. Your health care provider will tell you how to throw away used needles, syringes, tubing, and containers to avoid accidental injury.Signs of infection
    If you are receiving nalbuphine in your vein or under your skin, you need to know the symptoms of a catheter-related infection (an infection where the needle enters your vein or skin). If you experience any of these effects near your intravenous catheter, tell your health care provider as soon as possible:
  • tenderness
  • warmth
  • irritation
  • drainage
  • redness
  • swelling
  • pain

Drug Overview

Nubain belongs to the group of a Narcotic analgesic, anesthesia adjunct and opioid analgesic agent drug, commonly used for the treatment and relieves of the symptoms of pain due to certain disorders. The exact working mechanism of Nubain is not fully understood but it works by binding the brain receptors, relieving pain.

Nubain is more useful medicine for the treatment and relief of those patients who suffered to the problems of the severe pain which occurs due to several disorders.

Nubain is also used to relieve pain before and during surgery, including dental surgery.

Nubain always takes under doctor’s guidance. The recommended doses of Nubain will be different for different patients, according to the requirements of each patient; you continue to take it for as long as your doctor prescribes. If you can not tolerate the recommended dosage, your doctor can prescribe a dose that sufficient for you. Take Nubain exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Nubain is being manufactured by The Purdue Frederick Co. Nubain comes in category of drugs called also Nalbuphine and available in injection. Nubain may also be used for relieves other conditions that determined by your doctor or consultant.

Effects – How it works in the body

Nubain belongs to the group of a Narcotic analgesic, anesthesia adjunct and opioid analgesic agent drug, commonly used for the treatment and relieves of the symptoms of pain due to certain disorders. The exact working mechanism of Nubain is not fully understood but it works by binding the brain receptors, relieving pain. The feeling of pain and a person’s response to pain are also decreased. Nubain works by affecting the way the body senses pain.

Side effects

Possible side effects that occurs during the uses of Nubain:

  • Allergic reactions
  • Anxiety
  • Constipation
  • Depressed or irritable mood
  • Dizziness
  • Drowsiness
  • Light-headedness
  • Nausea
  • Sedation
  • Sweating
  • Vomiting
  • Agitation
  • Chills
  • Constipation
  • Depression
  • Diarrhea
  • Difficult urination disorientation
  • Dry mouth
  • Headache
  • High blood pressure
  • Hives
  • Itching
  • Low blood pressure
  • Mood changes
  • Nervousness
  • Rash
  • Sexual drive or performance problems
  • Slow heartbeat
  • Swelling due to fluid retention
  • Tremor
  • Unusual tiredness or weakness
  • Yellowing of the eyes or skin

Interactions

Although certain medicines should not be used together at all, so its your responsibilities that tell your doctor or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also you tell your doctor or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or addicted to illegal drugs. These may affect the working mechanism of Nubain. In these cases, your doctor may change the dose or teach precautions may be necessary. Therefore when you are taking Nubain, it is most important that your doctor or health care professional know if you are taking any of the following or other drugs:

  • Alcohol
  • Barbiturates
  • Benzodiazepines
  • Central nervous system (CNS) depressants medicine
  • Buprenorphine or similar medicines
  • Cimetidine
  • Erythromycin
  • Naltrexone
  • Certain analgesics such as Talwin, Stadol, and Buprenex
  • Drugs that control vomiting, such as Compazine and Tigan
  • Drugs classified as MAO inhibitors, such as the antidepressants Nardil and Parnate
  • Major tranquilizers such as Thorazine and Haldol
  • Muscle relaxants such as Flexeril and Valium
  • Sedatives such as Dalmane and Halcion
  • Tranquilizers such as Librium and Xanax
  • Water pills such as Diuril and Lasix

Counterindications

You shouldn’t use this medicine without consultation of doctor if you have an allergy to Nubain or any other ingredients of this medicine.

You shouldn’t use Nubain without consultation of doctor if you are suffering to the problem liver disease.

You shouldn’t use Nubain without consultation of doctor if you are suffering to the problem of Kidney disease.

You shouldn’t use Nubain without consultation of doctor if you are suffering to the problem of heart disease or blood disorders.

You shouldn’t use Nubain without consultation of doctor if you are suffering to the problems of lung disease.

You shouldn’t use Nubain without consultation of doctor if you are suffering to the problems of thyroid disease.

You shouldn’t use Nubain without consultation of doctor if you are suffering to the problems of alcoholism.

You shouldn’t use Nubain without consultation of doctor if you are suffering to the problems of prostatic hypertrophy (enlarged prostate).

You shouldn’t use Nubain without consultation of doctor if you are suffering to the problems of urinary problems.

You shouldn’t use Nubain without consultation of doctor if you are suffering to the problems of Brain tumor or Head injury.

You shouldn’t use Nubain without consultation of doctor if you are suffering to the problems of Gallbladder disease.

You shouldn’t use Nubain without consultation of doctor if you are suffering to the problems of Prostate disease.

You shouldn’t use Nubain without consultation of doctor if you are pregnant or plan to be pregnant.

You shouldn’t use Nubain without consultation of doctor if you are suffering to breastfeeding.

Similar drugs

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  • Astramorph PF
  • Buprenex
  • Demerol
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  • Nubain
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  • RMS
  • Roxanol
  • Roxanol Rescudose
  • Roxanol T
  • Epimorph (Canada)
  • Nubain-HP (Canada)
  • MS-IR (Canada)
  • Statex (Canada)
  • MST-Continus (Mexico)

Major drug Manufacturers

  • The Purdue Frederick Co.
  • Astra Zeneca Pharmaceuticals
  • Roche Pharmaceuticals
  • Lundbeck Pharmaceuticals
  • Janssen-Ortho Pharmaceuticals
  • Akorn Pharmaceuticals
  • Reckitt Benckiser Pharmaceuticals
  • Abbott Labs
  • Sanofi-Synthelabo Pharmaceuticals

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